Khoom noj khoom haus Khoom noj khoom haus qib Oleanolic Acid Hmoov
oleanolic acid yog dab tsi?
Oleanolic acid (OA), lub ntuj hydroxyl pentacyclic triterpenoid acid (HPTA) zoo ib yam li betulinic acid, ursolic acid;
Koj tuaj yeem nrhiav oleanolic acid nyob qhov twg?
Qee cov txiv hmab txiv ntoo xws li txiv apples, pomegranate, txiv qaub, bilberries, txiv ntseej muaj oleanolic acid.
| Tshuaj ntsuab | Cov ntsiab lus ntawm Oleanolic acid | Kev sim |
| Lub ci privet hais | 0.8028% | HPLC |
| Verbena Officinalis L | 0.071% - 0.086% | HPLC |
| Prunella vulgaris L | 3.47% -4.46% | HPLC |
| Hemsley Chinensis cog. | 1.5% ~ 2% | HPLC |
Tam sim no, suav tshuaj ntsuabHemsley Chinensis cogtseem yog cov khoom lag luam tshaj plaws rau kev rho tawm oleanolic acid.
Hemsley Chinensis cog.Taw qhia
Hemsleya chinensis cogn.yog ib tsob nroj nce toj xyoob ntoo, kuj yog tshuaj suav tshuaj.
- Tsev neeg: Cucurbitaceae
- Pawg: Gomphogyneae
- Hom: Hemsleya
- Hom: H. ntxim hlub
Cov tshuaj ntsuab tau muab faib rau hauv xeev Guangxi, Sichuan, Guizhou, Yunnan, Hubei, thiab lwm yam. Yug hauv hav zoov ntug hav zoov thiab hav zoov shrubs ntawm qhov siab txog 2,000 meters.
Cov khoom xyaw nquag: muaj Hemslolide Mal, Ma3, H1; Chikusetsusaponin-Iva; dihydro cucurbitacin F-25-acetate; dilydrocucurbitacin F; oleanolic acid-beta-Hlucosyloleanolate; Hemsamabilinin A; Cu-curbitacinⅡb-2-beta-D-glucopyranoside.
Extraction ntawm Oleanolic acid los ntawm Hemsleya Chinensis cogn.
BASIC analysis
| Yam khoom ntawm Kev Ntsuam Xyuas | Specification | Cov txiaj ntsig | Kev sim |
| Assay | ≥98.0% | 98.4% | HPLC |
| Organoleptic | |||
| Qhov tshwm sim | Hmoov | Ua raws | Organoleptic |
| Xim | Off-dawb crystalline hmoov | Ua raws | Organoleptic |
| tsw | Tsis muaj ntxhiab thiab tsis qab | Ua raws | Organoleptic |
| Cov yam ntxwv ntawm lub cev | |||
| Poob rau ziab | ≤ 0.5% | 0.01% | USP |
| Cov seem | ≤0.1% | 0.039% | USP |
| Kev sib hloov tshwj xeeb | 75.0° - 83.0° | 78.2° Nws | PIB 2010 |
| Cov hlau hnyav | |||
| Total Heavy Metals | 20 ppm Max | Ua raws | USPmethod II |
| Lead (Pb) | 3 ppm NM | Ua raws | ICP-MS |
| Arsenic (As) | 2 ppm NM | Ua raws | ICP-MS |
| Cadmium (Cd) | 1 ppm NMT | Ua raws | ICP-MS |
| Mercury (Hg) | 0.1ppm NMT | Ua raws | ICP-MS |
| Kev ntsuam xyuas microbiological | |||
| Tag Nrho Plate Count: | NMT 5,000 cfu/g | Ua raws | AOAC |
| Pwm & Pwm: | NMT 300 cfu/g | Ua raws | AOAC |
| Salmonella: | Tsis zoo | Ua raws | AOAC |
| E. Coli: | Tsis zoo | Ua raws | AOAC |
Muaj nuj nqi
Oleanolic Acid (ursolic acid) yog lub ntuj triterpenoid compound dav hauv cov nroj tsuag, xws li bearberry, txiv ntseej, blueberries, thiab lwm yam. Ntawm no yog qee qhov kev qhia txog Oleanolic Acid:
- Anti-inflammatory thiab antioxidant teebmeem:Ursolic acid muaj cov haujlwm tseem ceeb hauv kev tiv thaiv kab mob thiab antioxidant. Nws tuaj yeem txo cov kev mob tshwm sim, inhibit qhov kev tso tawm ntawm cov kab mob inflammatory, tshem tawm cov dawb radicals hauv lub cev, thiab txo kev puas tsuaj los ntawm oxidative kev nyuaj siab.
- Kev tiv thaiv daim siab:Ursolic acid muaj kev tiv thaiv ntawm daim siab. Nws txhawb lub siab cell regeneration thiab kho, txo txoj kev pheej hmoo ntawm daim siab puas. Ursolic acid tseem tuaj yeem tiv thaiv thiab kho cov kab mob siab xws li daim siab rog los ntawm kev tswj cov roj metabolism hauv lub siab.
- Kev tiv thaiv qog nqaij hlav:Ursolic acid muaj kev cuam tshuam rau qee cov qog hlwb. Nws tuaj yeem ua haujlwm los tiv thaiv qog nqaij hlav los ntawm kev tswj cov cell apoptosis, inhibiting kev loj hlob thiab cuam tshuam ntawm cov qog hlwb, thiab tswj cov kev taw qhia ntawm cov qog nqaij hlav cancer.
- Cov nyhuv hypoglycemic:Ursolic acid muaj qee yam cuam tshuam rau txo cov ntshav qab zib thiab txhim kho pancreatic islet cell ua haujlwm. Nws txhawb kev tsim cov tshuaj insulin thiab txhim kho kev nkag siab ntawm insulin, yog li pab tswj ntshav qab zib thiab tiv thaiv cov teeb meem cuam tshuam.
- Antibacterial thiab antiviral kev ua haujlwm:Ursolic acid muaj qee yam tshuaj tua kab mob thiab tshuaj tua kab mob tiv thaiv ntau yam kab mob thiab kab mob. Nws inhibits kev loj hlob thiab rov ua dua ntawm cov kab mob thiab cov kab mob, txo qhov kev pheej hmoo ntawm kev kis kab mob thiab kab mob.
Tsis tas li ntawd, ursolic acid tau pom tias muaj cov tawv nqaij tiv thaiv, antioxidant zog, thiab tiv thaiv kab mob plawv ischemic.
